A simple three-component synthesis of 3-amino-5-arylpyridazine-4-carbonitriles

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South African Journal of Chemistry

On-line version ISSN 1996-840XPrint version ISSN 0379-4350

Abstract

KHALAFY, J.; RIMAZ, M.; FARAJZADEH, S. and EZZATI, M.. A simple three-component synthesis of 3-amino-5-arylpyridazine-4-carbonitriles. S.Afr.j.chem. (Online) [online]. 2013, vol.66, pp.00-00. ISSN 1996-840X.

New 3-amino-5-arylpyridazine-4-carbonitriles have been synthesized by a one-pot three-component reaction of malononitrile with arylglyoxals in the presence of hydrazine hydrate at room temperature in water and ethanol.

Keywords : Arylglyoxals; arylpyridazines; hydrazine hydrate; one-pot; malononitrile.

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