Services on Demand
Article
Indicators
Related links
- Cited by Google
- Similars in Google
Share
Southern African Journal of HIV Medicine
On-line version ISSN 2078-6751
Print version ISSN 1608-9693
Abstract
SWART, Leanne; SCHAPKAITZ, Elise and BAIDEN, Anima. A case of a drug reaction to sulfasalazine in a patient infected with HIV. South. Afr. j. HIV med. (Online) [online]. 2018, vol.19, n.1, pp.1-3. ISSN 2078-6751. http://dx.doi.org/10.4102/sajhivmed.v19i1.829.
INTRODUCTION: The diagnosis of drug reaction with eosinophilia and systemic symptoms (DRESS) in human immunodeficiency virus (HIV) patients on multiple drugs with concomitant disorders presents a diagnostic challenge PATIENT PRESENTATION: We describe a case of a drug reaction to sulfasalazine in a 46 year old HIV-infected female with concurrent rheumatoid arthritis which presented atypically with a marked peripheral blood plasmacytosis mimicking a lymphoproliferative neoplasm MANAGEMENT AND OUTCOME: A diagnosis of DRESS was made in conjunction with the laboratory and clinical presenting findings. Sulfasalazine was immediately discontinued. The mucocutaneous rash and systemic symptoms (which included fever, lymphadenopathy and multi-organ dysfunction) resolved with supportive treatment. This included topical and systemic corticosteroids. CONCLUSION: In conclusion, it is important to consider drug reactions when evaluating patients infected with HIV