Abstract

MALINGA, Sibongiseni; KHAN, Aabida  and  ARCHARY, Moherndran. Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal. South. Afr. j. HIV med. (Online) [online]. 2023, vol.24, n.1, pp.1-4. ISSN 2078-6751.  https://doi.org/10.4102/sajhivmed.v24i1.1458.

We report a case of dolutegravir resistance in KwaZulu-Natal in a 13-year-old male two years after starting dolutegravir. Resistance most likely developed due to poor adherence as a result of psychosocial issues. This case highlights the importance of the role of the family unit in impacting adherence and close monitoring of treatment-experienced patients with virologic failure following switching to dolutegravir-based regimens.

Keywords : paediatrics; dolutegravir; DTG; resistance; HIV; adolescence.

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