Abstract

BRANDI, Nicolò; BARTALENA, Laura; MOSCONI, Cristina  and  GOLFIERI, Rita. A unique case of miliary pulmonary tuberculosis induced by bacillus Calmette-Guérin intravesical instillation with COVID-19 superinfection. S. Afr. J. radiol. (Online) [online]. 2021, vol.25, n.1, pp.1-3. ISSN 2078-6778.  https://doi.org/10.4102/sajr.v25i1.2122.

Intravesical instillation of Bacillus Calmette-Guérin (BCG) is used as an adjuvant treatment of bladder cancer. Systemic BCG infection occurs in less than 1% of cases, and pulmonary involvement is even rarer (0.3% - 0.7%), with a favourable prognosis. A 78-year-old male developed miliary tuberculosis (TB) secondary to intravesical BCG treatment and subsequent coronavirus disease 2019 (COVID-19) superinfection that led to patient death. High awareness amongst clinicians is needed to proceed with immediate appropriate therapy in these patients, especially during the COVID-19 pandemic

Keywords : tuberculosis; BCG; COVID-19; SARS-CoV-2; CT.

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