Abstract

NSOBYA, Sam L.; HEWETT, Paul C.; KALIBALA, Sam  and  MENSCH, Barbara S.. Performance of Kalon herpes simplex virus 2 assay using dried blood spots among young women in Uganda. Afr. J. Lab. Med. [online]. 2016, vol.5, n.1, pp.1-4. ISSN 2225-2010.  http://dx.doi.org/10.4102/ajlm.v5i1.429.

This study evaluated the performance of the Kalon Biological HSV2 IgG enzyme-linked immunosorbent assay (Kalon Biological Ltd, Surrey, United Kingdom) on dried blood spots (DBS) of various dilutions compared with plasma from young women aged 18-24 years in Uganda. We estimated the sensitivity and specificity of three DBS dilutions using plasma as the reference. All three evaluated DBS dilutions yielded low sensitivities and specificities, with DBS 1:2 yielding the highest concurrence. Other herpes simplex virus type 2 assays should be examined with regard to their utility for testing DBS.

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