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Southern African Journal of HIV Medicine
versão On-line ISSN 2078-6751
versão impressa ISSN 1608-9693
Resumo
MALINGA, Sibongiseni; KHAN, Aabida e ARCHARY, Moherndran. Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal. South. Afr. j. HIV med. (Online) [online]. 2023, vol.24, n.1, pp.1-4. ISSN 2078-6751. http://dx.doi.org/10.4102/sajhivmed.v24i1.1458.
We report a case of dolutegravir resistance in KwaZulu-Natal in a 13-year-old male two years after starting dolutegravir. Resistance most likely developed due to poor adherence as a result of psychosocial issues. This case highlights the importance of the role of the family unit in impacting adherence and close monitoring of treatment-experienced patients with virologic failure following switching to dolutegravir-based regimens.
Palavras-chave : paediatrics; dolutegravir; DTG; resistance; HIV; adolescence.