RESEARCH ARTICLE

 

A new sterol diglycoside from Conyza floribunda

 

 

Sylvia A. Opiyo^I; Joseph A. Ogur^I; Lawrence O.A. Manguro^I; Lutz F. Tietze^II; Heiko Schuster^II

^IDepartment of Chemistry, Maseno University, P. O. Box 333, Maseno, Kenya
^IIInstitute for Organic and Biomolecular Chemistry, Georg-August University, Tamannstrasse 2, 37007-Göttingen, Germany

 

 

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ABSTRACT

Chemical investigation of CH₂Cl₂ and MeOH extracts of Conyza floribunda have led to the isolation of (24S)-ethylcholesta-5, 22E, 25-trien-3-0-glucosyl (1" → 4')-rhamnoside (1), (24S)-ethylcholesta-5,25-dien-3-0-β-glucoside (2), cyasterone (3), stigmasta 5,22-dien-3-acetate (4), stigmasta 5,22-dien-3-ol (5), spinasta 7,22-dien-3-ol (6), 3-oxofriedooleanane (7), 3-hydroxyfriedooleanane (8), 3-acetoxyfriedooleanane (9), betullinic acid (10), quercetin 3-0-β-glucoside (11), quercetin (12), myricetin (13) and kaempferol (14). Their structures were determined using spectroscopic and physical methods as well as comparison with data available in the literature.

Keywords: Conyza floribunda, asteraceae, triterpenes, sterols, flavonols

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Acknowledgements

The authors are grateful to Maseno University Deans' Committee for partially providing funds for the research. The German Academic Exchange Service (DAAD) is sincerely thanked for the fellowship awarded to L.O.A. Manguro, which enabled most of the analyses to be done at Georg-August University, Göttingen, Germany. The National Museum of Kenya is acknowledged for identification of the plant.

 

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Received 7 November 2008
Revised 24 July 2009
Accepted 2 September 2009

 

 

* To whom correspondence should be addressed. E-mail: sylvopiyo@yahoo.com