SciELO - Scientific Electronic Library Online

vol.66The synthesis of substituted piperazine-cholesterol conjugates for use as components of nucleic acid transfection lipoplexesNatural products research in South Africa: End of an era on land or the beginning of an endless opportunity in the sea? author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand



Related links

  • On index processCited by Google
  • On index processSimilars in Google


South African Journal of Chemistry

On-line version ISSN 1996-840X
Print version ISSN 0379-4350


BROMLEY, Candice L. et al. Halogenated oxindole and indoles from the South African marine ascidian Distaplia skoogi. S.Afr.j.chem. (Online) [online]. 2013, vol.66, pp.00-00. ISSN 1996-840X.

The known 3,6-dibromoindole (1), 6-bromo-3-chloroindole (2) and 6-bromo-2-oxindole (3) were isolated from the marine ascidian (sea squirt) Distapia skoogi collected from Algoa Bay, South Africa. Standard spectroscopic techniques were used to elucidate the structures of 1-3. All three compounds were found to be moderately cytotoxic to metastatic MDA-MB-231 breast cancer cells.

Keywords : Distaplia skoogi; ascidian; indole; oxindole.

        · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License